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Investigating Synthetic Oligonucleotide Targeting of Mir31 in Duchenne Muscular Dystrophy

Exon-skipping via synthetic antisense oligonucleotides represents one of the most promising potential therapies for Duchenne muscular dystrophy (DMD), yet this approach is highly sequence-specific and thus each oligonucleotide is of benefit to only a subset of patients. The discovery that dystrophin...

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Detalles Bibliográficos
Autores principales: Hildyard, John CW, Wells, Dominic J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972457/
https://www.ncbi.nlm.nih.gov/pubmed/27525173
http://dx.doi.org/10.1371/currents.md.99d88e72634387639707601b237467d7