Complement and Antibody-mediated Enhancement of Red Blood Cell Invasion and Growth of Malaria Parasites

Plasmodium falciparum malaria is a deadly pathogen. The invasion of red blood cells (RBCs) by merozoites is a target for vaccine development. Although anti-merozoite antibodies can block invasion in vitro, there is no efficacy in vivo. To explain this discrepancy we hypothesized that complement acti...

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Detalles Bibliográficos
Autores principales: Biryukov, Sergei, Angov, Evelina, Landmesser, Mary E., Spring, Michele D., Ockenhouse, Christian F., Stoute, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972486/
https://www.ncbi.nlm.nih.gov/pubmed/27333049
http://dx.doi.org/10.1016/j.ebiom.2016.05.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972486/
https://www.ncbi.nlm.nih.gov/pubmed/27333049
http://dx.doi.org/10.1016/j.ebiom.2016.05.015

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