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A Mouse Model of Hyperproliferative Human Epithelium Validated by Keratin Profiling Shows an Aberrant Cytoskeletal Response to Injury

A validated animal model would assist with research on the immunological consequences of the chronic expression of stress keratins KRT6, KRT16, and KRT17, as observed in human pre-malignant hyperproliferative epithelium. Here we examine keratin gene expression profile in skin from mice expressing th...

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Detalles Bibliográficos
Autores principales: Zhussupbekova, Samal, Sinha, Rohit, Kuo, Paula, Lambert, Paul F., Frazer, Ian H., Tuong, Zewen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972546/
https://www.ncbi.nlm.nih.gov/pubmed/27333029
http://dx.doi.org/10.1016/j.ebiom.2016.06.011