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The Dynamic Role of the IL-33/ST2 Axis in Chronic Viral-infections: Alarming and Adjuvanting the Immune Response

Interleukin 33 (IL-33), a member of the IL-1 family, is constitutively expressed in epithelial and in endothelial cells at barrier sites, acting as a danger signal and adjuvanting the immune response following tissue damage and infection. Originally implicated in allergy, IL-33 is also known to be i...

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Detalles Bibliográficos
Autores principales: Mehraj, Vikram, Ponte, Rosalie, Routy, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972565/
https://www.ncbi.nlm.nih.gov/pubmed/27397514
http://dx.doi.org/10.1016/j.ebiom.2016.06.047