Bimodal expression of PHO84 is modulated by early termination of antisense transcription

Many S. cerevisiae genes encode antisense transcripts some of which are unstable and degraded by the exosome component Rrp6. Loss of Rrp6 results in the accumulation of long PHO84 antisense RNAs and repression of sense transcription through PHO84 promoter deacetylation. We used single molecule resol...

Descripción completa

Detalles Bibliográficos
Autores principales: Castelnuovo, Manuele, Rahman, Samir, Guffanti, Elisa, Infantino, Valentina, Stutz, Françoise, Zenklusen, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972572/
https://www.ncbi.nlm.nih.gov/pubmed/23770821
http://dx.doi.org/10.1038/nsmb.2598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972572/
https://www.ncbi.nlm.nih.gov/pubmed/23770821
http://dx.doi.org/10.1038/nsmb.2598

Ejemplares similares