Defining the structural relationship between kainate receptor deactivation and desensitization

Desensitization is an important mechanism that curtails the activity of ligand-gated ion-channels (LGICs). Although the structural basis of desensitization is not fully resolved, it is thought to be governed by the physicochemical properties of the bound ligand. Here, we show the importance of an al...

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Detalles Bibliográficos
Autores principales: Dawe, G. Brent, Musgaard, Maria, Andrews, Elizabeth D., Daniels, Bryan A., Aurousseau, Mark R.P., Biggin, Philip C., Bowie, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972573/
https://www.ncbi.nlm.nih.gov/pubmed/23955023
http://dx.doi.org/10.1038/nsmb.2654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972573/
https://www.ncbi.nlm.nih.gov/pubmed/23955023
http://dx.doi.org/10.1038/nsmb.2654

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