High-resolution structure of TBP with TAF1 reveals anchoring patterns in transcriptional regulation

The general transcription factor TFIID provides a regulatory platform for transcription initiation. Here we present the crystal structure (1.97 Å) and NMR analysis of yeast TAF1 N-terminal domains TAND1 and TAND2 when bound to yeast TBP, together with mutational data. The yTAF1-TAND1, which in itsel...

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Detalles Bibliográficos
Autores principales: Anandapadamanaban, Madhanagopal, Andresen, Cecilia, Helander, Sara, Ohyama, Yoshifumi, Siponen, Marina I., Lundström, Patrik, Kokubo, Tetsuro, Ikura, Mitsuhiko, Moche, Martin, Sunnerhagen, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972576/
https://www.ncbi.nlm.nih.gov/pubmed/23851461
http://dx.doi.org/10.1038/nsmb.2611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972576/
https://www.ncbi.nlm.nih.gov/pubmed/23851461
http://dx.doi.org/10.1038/nsmb.2611

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