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High-resolution structure of TBP with TAF1 reveals anchoring patterns in transcriptional regulation
The general transcription factor TFIID provides a regulatory platform for transcription initiation. Here we present the crystal structure (1.97 Å) and NMR analysis of yeast TAF1 N-terminal domains TAND1 and TAND2 when bound to yeast TBP, together with mutational data. The yTAF1-TAND1, which in itsel...
Autores principales: | Anandapadamanaban, Madhanagopal, Andresen, Cecilia, Helander, Sara, Ohyama, Yoshifumi, Siponen, Marina I., Lundström, Patrik, Kokubo, Tetsuro, Ikura, Mitsuhiko, Moche, Martin, Sunnerhagen, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972576/ https://www.ncbi.nlm.nih.gov/pubmed/23851461 http://dx.doi.org/10.1038/nsmb.2611 |
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