Netupitant, a Potent and Highly Selective NK(1) Receptor Antagonist, Alleviates Acetic Acid-Induced Bladder Overactivity in Anesthetized Guinea-Pigs

Introduction. Tachykinins potently contract the isolated urinary bladder from a number of animal species and play an important role in the regulation of the micturition reflex. On the guinea-pig isolated urinary bladder we examined the effects of a new potent and selective NK(1) receptor antagonist...

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Detalles Bibliográficos
Autores principales: Palea, Stefano, Guilloteau, Véronique, Rekik, Moéz, Lovati, Emanuela, Guerard, Marc, Guardia, Maria-Alba, Lluel, Philippe, Pietra, Claudio, Yoshiyama, Mitsuharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972833/
https://www.ncbi.nlm.nih.gov/pubmed/27540361
http://dx.doi.org/10.3389/fphar.2016.00234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972833/
https://www.ncbi.nlm.nih.gov/pubmed/27540361
http://dx.doi.org/10.3389/fphar.2016.00234

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