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TLR9 re-expression in cancer cells extends the S-phase and stabilizes p16(INK4a) protein expression
Toll-like receptor 9 (TLR9) recognizes bacterial, viral or cell damage-associated DNA, which initiates innate immune responses. We have previously shown that TLR9 expression is downregulated in several viral induced cancers including HPV16-induced cervical neoplasia. Findings supported that downregu...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972902/ https://www.ncbi.nlm.nih.gov/pubmed/27454079 http://dx.doi.org/10.1038/oncsis.2016.49 |