Comparative transcriptomic analysis reveals the oncogenic fusion protein PAX3-FOXO1 globally alters mRNA and miRNA to enhance myoblast invasion

Rhabdomyosarcoma, one of the most common childhood sarcomas, is comprised of two main subtypes, embryonal and alveolar (ARMS). ARMS, the more aggressive subtype, is primarily characterized by the t(2;13)(p35;p14) chromosomal translocation, which fuses two transcription factors, PAX3 and FOXO1 to gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Loupe, J M, Miller, P J, Bonner, B P, Maggi, E C, Vijayaraghavan, J, Crabtree, J S, Taylor, C M, Zabaleta, J, Hollenbach, A D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972903/
https://www.ncbi.nlm.nih.gov/pubmed/27454080
http://dx.doi.org/10.1038/oncsis.2016.53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972903/
https://www.ncbi.nlm.nih.gov/pubmed/27454080
http://dx.doi.org/10.1038/oncsis.2016.53

Ejemplares similares