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Tolerance to Ethanol or Nicotine Results in Increased Ethanol Self-Administration and Long-Term Depression in the Dorsolateral Striatum

Ethanol (EtOH) and nicotine are the most widely coabused drugs. Tolerance to EtOH intoxication, including motor impairment, results in greater EtOH consumption and may result in a greater likelihood of addiction. Previous studies suggest that cross-tolerance between EtOH and nicotine may contribute...

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Detalles Bibliográficos
Autores principales: Abburi, Chandrika, Wolfman, Shannon L., Metz, Ryan A. E., Kamber, Rinya, McGehee, Daniel S., McDaid, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972936/
https://www.ncbi.nlm.nih.gov/pubmed/27517088
http://dx.doi.org/10.1523/ENEURO.0112-15.2016