Phorbol ester-mediated re-expression of endogenous LAT adapter in J.CaM2 cells: a model for dissecting drivers and blockers of LAT transcription

Linker for activation of T cells (LAT) is a raft-associated, transmembrane adapter protein critical for T-cell development and function. LAT expression is transiently upregulated upon T-cell receptor (TCR) engagement, but molecular mechanisms conveying TCR signaling to enhanced LAT transcription are...

Descripción completa

Detalles Bibliográficos
Autores principales: Marek-Bukowiec, K, Aguado, E, Miazek, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972999/
https://www.ncbi.nlm.nih.gov/pubmed/27278128
http://dx.doi.org/10.1038/gene.2016.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972999/
https://www.ncbi.nlm.nih.gov/pubmed/27278128
http://dx.doi.org/10.1038/gene.2016.25

Ejemplares similares