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Casein kinase 1α has a non-redundant and dominant role within the CK1 family in melanoma progression

BACKGROUND: We previously identified CK1α as a novel tumor suppressor in melanoma and reported that the loss of CK1α leads to increased proliferation and invasive growth of melanoma cells by strong activation of the Wnt/β-catenin signaling pathway. METHODS: In this study we analyzed expression and t...

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Detalles Bibliográficos
Autores principales: Sinnberg, Tobias, Wang, Jun, Sauer, Birgit, Schittek, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973074/
https://www.ncbi.nlm.nih.gov/pubmed/27488834
http://dx.doi.org/10.1186/s12885-016-2643-0