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Repression of the autophagic response sensitises lung cancer cells to radiation and chemotherapy

BACKGROUND: The cellular autophagic response to radiation is complex. Various cells and tissues respond differentially to radiation, depending on both the dose of exposure and the time post irradiation. In the current study, we determined the autophagosomal and lysosomal response to radiation in lun...

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Detalles Bibliográficos
Autores principales: Karagounis, Ilias V, Kalamida, Dimitra, Mitrakas, Achilleas, Pouliliou, Stamatia, Liousia, Maria V, Giatromanolaki, Alexandra, Koukourakis, Michael I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973160/
https://www.ncbi.nlm.nih.gov/pubmed/27380135
http://dx.doi.org/10.1038/bjc.2016.202