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Suppression of amyloid fibrils using the GroEL apical domain

In E. coli cells, rescue of non-native proteins and promotion of native state structure is assisted by the chaperonin GroEL. An important key to this activity lies in the structure of the apical domain of GroEL (GroEL-AD) (residue 191–376), which recognizes and binds non-native protein molecules thr...

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Detalles Bibliográficos
Autores principales: Ojha, Bimlesh, Fukui, Naoya, Hongo, Kunihiro, Mizobata, Tomohiro, Kawata, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973282/
https://www.ncbi.nlm.nih.gov/pubmed/27488469
http://dx.doi.org/10.1038/srep31041