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Nucleolar organizer regions: genomic ‘dark matter’ requiring illumination

Nucleoli form around tandem arrays of a ribosomal gene repeat, termed nucleolar organizer regions (NORs). During metaphase, active NORs adopt a characteristic undercondensed morphology. Recent evidence indicates that the HMG-box-containing DNA-binding protein UBF (upstream binding factor) is directl...

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Detalles Bibliográficos
Autor principal: McStay, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973289/
https://www.ncbi.nlm.nih.gov/pubmed/27474438
http://dx.doi.org/10.1101/gad.283838.116