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Nucleolar organizer regions: genomic ‘dark matter’ requiring illumination
Nucleoli form around tandem arrays of a ribosomal gene repeat, termed nucleolar organizer regions (NORs). During metaphase, active NORs adopt a characteristic undercondensed morphology. Recent evidence indicates that the HMG-box-containing DNA-binding protein UBF (upstream binding factor) is directl...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973289/ https://www.ncbi.nlm.nih.gov/pubmed/27474438 http://dx.doi.org/10.1101/gad.283838.116 |