Oncogenic transformation of Drosophila somatic cells induces a functional piRNA pathway

Germline genes often become re-expressed in soma-derived human cancers as “cancer/testis antigens” (CTAs), and piRNA (PIWI-interacting RNA) pathway proteins are found among CTAs. However, whether and how the piRNA pathway contributes to oncogenesis in human neoplasms remain poorly understood. We fou...

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Detalles Bibliográficos
Autores principales: Fagegaltier, Delphine, Falciatori, Ilaria, Czech, Benjamin, Castel, Stephane, Perrimon, Norbert, Simcox, Amanda, Hannon, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973292/
https://www.ncbi.nlm.nih.gov/pubmed/27474441
http://dx.doi.org/10.1101/gad.284927.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973292/
https://www.ncbi.nlm.nih.gov/pubmed/27474441
http://dx.doi.org/10.1101/gad.284927.116

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