A conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation

RNA degradation is tightly regulated to selectively target aberrant RNAs, including viral RNA, but this regulation is incompletely understood. Through RNAi screening in Drosophila cells, we identified the 3′-to-5′ RNA exosome and two components of the exosome cofactor TRAMP (Trf4/5–Air1/2–Mtr4 polya...

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Detalles Bibliográficos
Autores principales: Molleston, Jerome M., Sabin, Leah R., Moy, Ryan H., Menghani, Sanjay V., Rausch, Keiko, Gordesky-Gold, Beth, Hopkins, Kaycie C., Zhou, Rui, Jensen, Torben Heick, Wilusz, Jeremy E., Cherry, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973295/
https://www.ncbi.nlm.nih.gov/pubmed/27474443
http://dx.doi.org/10.1101/gad.284604.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973295/
https://www.ncbi.nlm.nih.gov/pubmed/27474443
http://dx.doi.org/10.1101/gad.284604.116

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