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A polymorphic minisatellite region of BORIS regulates gene expression and its rare variants correlate with lung cancer susceptibility

Aberrant expression of BORIS/CTCFL (Brother of the Regulator of Imprinted Sites/CTCF-like protein) is reported in different malignancies. In this study, we characterized the entire promoter region of BORIS/CTCFL, including the CpG islands, to assess the relationship between BORIS expression and lung...

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Detalles Bibliográficos
Autores principales: Yoon, Se-Lyun, Roh, Yun-Gil, Chu, In-Sun, Heo, Jeonghoon, Kim, Seung Il, Chang, Heekyung, Kang, Tae-Hong, Chung, Jin Woong, Koh, Sang Seok, Larionov, Vladimir, Leem, Sun-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973313/
https://www.ncbi.nlm.nih.gov/pubmed/27416782
http://dx.doi.org/10.1038/emm.2016.50