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Genetic–pathologic characterization of myeloproliferative neoplasms

Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders characterized by the proliferation of one or more myeloid lineages. The current study demonstrates that three driver mutations were detected in 82.6% of 407 MPNs with a mutation distribution of JAK2 in 275 (67.6%), CALR...

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Detalles Bibliográficos
Autores principales: Kim, Yonggoo, Park, Joonhong, Jo, Irene, Lee, Gun Dong, Kim, Jiyeon, Kwon, Ahlm, Choi, Hayoung, Jang, Woori, Chae, Hyojin, Han, Kyungja, Eom, Ki-Seong, Cho, Byung-Sik, Lee, Sung-Eun, Yang, Jinyoung, Shin, Seung-Hwan, Kim, Hyunjung, Ko, Yoon Ho, Park, Haeil, Jin, Jong Youl, Lee, Seungok, Jekarl, Dong Wook, Yahng, Seung-Ah, Kim, Myungshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973314/
https://www.ncbi.nlm.nih.gov/pubmed/27444979
http://dx.doi.org/10.1038/emm.2016.55