The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death

The 26S proteasome is a large, ∼2.5 MDa, multi-catalytic ATP-dependent protease complex that serves as the degrading arm of the ubiquitin system, which is the major pathway for regulated degradation of cytosolic, nuclear and membrane proteins in all eukaryotic organisms.

Detalles Bibliográficos
Autores principales: Livneh, Ido, Cohen-Kaplan, Victoria, Cohen-Rosenzweig, Chen, Avni, Noa, Ciechanover, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973335/
https://www.ncbi.nlm.nih.gov/pubmed/27444871
http://dx.doi.org/10.1038/cr.2016.86

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973335/
https://www.ncbi.nlm.nih.gov/pubmed/27444871
http://dx.doi.org/10.1038/cr.2016.86

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