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Tumorigenic potential is restored during differentiation in fusion-reprogrammed cancer cells

Detailed understanding of the mechanistic steps underlying tumor initiation and malignant progression is critical for insights of potentially novel therapeutic modalities. Cellular reprogramming is an approach of particular interest because it can provide a means to reset the differentiation state o...

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Detalles Bibliográficos
Autores principales: Yao, J, Zhang, L, Hu, L, Guo, B, Hu, X, Borjigin, U, Wei, Z, Chen, Y, Lv, M, Lau, J T Y, Wang, X, Li, G, Hu, Y-P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973342/
https://www.ncbi.nlm.nih.gov/pubmed/27468690
http://dx.doi.org/10.1038/cddis.2016.189