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Mps1 kinase regulates tumor cell viability via its novel role in mitochondria

Targeting mitotic kinase monopolar spindle 1 (Mps1) for tumor therapy has been investigated for many years. Although it was suggested that Mps1 regulates cell viability through its role in spindle assembly checkpoint (SAC), the underlying mechanism remains less defined. In an endeavor to reveal the...

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Detalles Bibliográficos
Autores principales: Zhang, X, Ling, Y, Guo, Y, Bai, Y, Shi, X, Gong, F, Tan, P, Zhang, Y, Wei, C, He, X, Ramirez, A, Liu, X, Cao, C, Zhong, H, Xu, Q, Ma, R Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973343/
https://www.ncbi.nlm.nih.gov/pubmed/27383047
http://dx.doi.org/10.1038/cddis.2016.193