DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrity

EZH2 is a histone methyltransferase whose functions in stem cells and tumor cells are well established. Accumulating evidence shows that EZH2 has critical roles in T cells and could be a promising therapeutic target for several immune diseases. To further reveal the novel functions of EZH2 in human...

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Detalles Bibliográficos
Autores principales: Wang, Y, Sun, H, Wang, J, Wang, H, Meng, L, Xu, C, Jin, M, Wang, B, Zhang, Y, Zhu, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973345/
https://www.ncbi.nlm.nih.gov/pubmed/27468692
http://dx.doi.org/10.1038/cddis.2016.198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973345/
https://www.ncbi.nlm.nih.gov/pubmed/27468692
http://dx.doi.org/10.1038/cddis.2016.198

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