The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation

Both clinical and experimental evidence have firmly established that chronic pancreatitis, in particular in the context of Kras oncogenic mutations, predisposes to pancreatic ductal adenocarcinoma (PDAC). However, the repertoire of molecular mediators of pancreatitis involved in Kras-mediated initia...

Descripción completa

Detalles Bibliográficos
Autores principales: Loncle, C, Molejon, M I, Lac, S, Tellechea, J I, Lomberk, G, Gramatica, L, Fernandez Zapico, M F, Dusetti, N, Urrutia, R, Iovanna, J L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973346/
https://www.ncbi.nlm.nih.gov/pubmed/27415425
http://dx.doi.org/10.1038/cddis.2016.202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973346/
https://www.ncbi.nlm.nih.gov/pubmed/27415425
http://dx.doi.org/10.1038/cddis.2016.202

Ejemplares similares