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WASH has a critical role in NK cell cytotoxicity through Lck-mediated phosphorylation

Natural killer (NK) cells are important effector cells of the innate immune system to kill certain virus-infected and transformed cells. Wiskott–Aldrich Syndrome protein (WASP) and SCAR homolog (WASH) has been identified as a member of WASP family proteins implicated in regulating the cytoskeletal r...

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Detalles Bibliográficos
Autores principales: Huang, L, Zhu, P, Xia, P, Fan, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973352/
https://www.ncbi.nlm.nih.gov/pubmed/27441653
http://dx.doi.org/10.1038/cddis.2016.212