Proton pump inhibitors protect mice from acute systemic inflammation and induce long-term cross-tolerance

Incidence of sepsis is increasing, representing a tremendous burden for health-care systems. Death in acute sepsis is attributed to hyperinflammatory responses, but the underlying mechanisms are still unclear. We report here that proton pump inhibitors (PPIs), which block gastric acid secretion, sel...

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Detalles Bibliográficos
Autores principales: Balza, E, Piccioli, P, Carta, S, Lavieri, R, Gattorno, M, Semino, C, Castellani, P, Rubartelli, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973356/
https://www.ncbi.nlm.nih.gov/pubmed/27441656
http://dx.doi.org/10.1038/cddis.2016.218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973356/
https://www.ncbi.nlm.nih.gov/pubmed/27441656
http://dx.doi.org/10.1038/cddis.2016.218

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