Egg antigen p40 of Schistosoma japonicum promotes senescence in activated hepatic stellate cells by activation of the STAT3/p53/p21 pathway

Liver fibrosis is a serious disease that is characterized by the excess deposition of extracellular matrix (ECM) components. Activated hepatic stellate cells (HSCs) are a major source of ECM and serve as a key regulator in liver fibrogenesis. Inactivation of HSCs is essential for liver fibrotic regr...

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Detalles Bibliográficos
Autores principales: Chen, Jinling, Xu, Tianhua, Zhu, Dandan, Wang, Jianxin, Huang, Caiqun, Lyu, Lei, Hu, Bin, Sun, Wei, Duan, Yinong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973363/
https://www.ncbi.nlm.nih.gov/pubmed/27468691
http://dx.doi.org/10.1038/cddis.2016.228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973363/
https://www.ncbi.nlm.nih.gov/pubmed/27468691
http://dx.doi.org/10.1038/cddis.2016.228

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