Venous thromboembolism risk associated with protracted work- and computer-related seated immobility: A case-control study

OBJECTIVE: To examine the association between venous thromboembolism and prolonged work- and computer-related seated immobility. DESIGN: A case-control study. PARTICIPANTS AND SETTING: Cases were 200 patients attending venous thromboembolism clinics with a history of deep vein thrombosis and/or pulm...

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Autores principales: Braithwaite, Irene, Healy, Bridget, Cameron, Laird, Weatherall, Mark, Beasley, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973402/
https://www.ncbi.nlm.nih.gov/pubmed/27540486
http://dx.doi.org/10.1177/2054270416632670
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author Braithwaite, Irene
Healy, Bridget
Cameron, Laird
Weatherall, Mark
Beasley, Richard
author_facet Braithwaite, Irene
Healy, Bridget
Cameron, Laird
Weatherall, Mark
Beasley, Richard
author_sort Braithwaite, Irene
collection PubMed
description OBJECTIVE: To examine the association between venous thromboembolism and prolonged work- and computer-related seated immobility. DESIGN: A case-control study. PARTICIPANTS AND SETTING: Cases were 200 patients attending venous thromboembolism clinics with a history of deep vein thrombosis and/or pulmonary embolism in the past six months, and controls were 200 patients treated in fracture clinic for an upper limb injury in the past six months. MAIN OUTCOME MEASURES: Logistic regression was used to estimate the association between venous thromboembolism and prolonged work- and computer-related seated immobility in the 28 days before the index event. Prolonged work- and computer-related seated immobility was defined firstly as a categorical variable with at least 10 h seated in a 24-h period, including at least 2 h without getting up; and secondly as the actual time spent seated in a 24-h period. RESULTS: Prolonged work- and computer-related seated immobility (categorical variable) was present in 36 (18%) cases and 31 (15.5%) controls. In multivariate analysis, there was no significant association between prolonged seated immobility and venous thromboembolism, odds ratio 1.18 (95% CI 0.56 to 2.48), P = 0.67. For the mean and maximum number of hours seated in a 24-h period, the odds ratios for the association per additional hour seated with venous thromboembolism were 1.08 (95% CI 1.01 to 1.6), P = 0.02 and 1.04 (95% CI 0.99 to 1.09), P = 0.08, respectively. CONCLUSION: This study found a weak association between venous thromboembolism and prolonged work- and computer-related seated immobility, with increasing mean hours seated associated with a higher risk of venous thromboembolism.
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spelling pubmed-49734022016-08-18 Venous thromboembolism risk associated with protracted work- and computer-related seated immobility: A case-control study Braithwaite, Irene Healy, Bridget Cameron, Laird Weatherall, Mark Beasley, Richard JRSM Open Research OBJECTIVE: To examine the association between venous thromboembolism and prolonged work- and computer-related seated immobility. DESIGN: A case-control study. PARTICIPANTS AND SETTING: Cases were 200 patients attending venous thromboembolism clinics with a history of deep vein thrombosis and/or pulmonary embolism in the past six months, and controls were 200 patients treated in fracture clinic for an upper limb injury in the past six months. MAIN OUTCOME MEASURES: Logistic regression was used to estimate the association between venous thromboembolism and prolonged work- and computer-related seated immobility in the 28 days before the index event. Prolonged work- and computer-related seated immobility was defined firstly as a categorical variable with at least 10 h seated in a 24-h period, including at least 2 h without getting up; and secondly as the actual time spent seated in a 24-h period. RESULTS: Prolonged work- and computer-related seated immobility (categorical variable) was present in 36 (18%) cases and 31 (15.5%) controls. In multivariate analysis, there was no significant association between prolonged seated immobility and venous thromboembolism, odds ratio 1.18 (95% CI 0.56 to 2.48), P = 0.67. For the mean and maximum number of hours seated in a 24-h period, the odds ratios for the association per additional hour seated with venous thromboembolism were 1.08 (95% CI 1.01 to 1.6), P = 0.02 and 1.04 (95% CI 0.99 to 1.09), P = 0.08, respectively. CONCLUSION: This study found a weak association between venous thromboembolism and prolonged work- and computer-related seated immobility, with increasing mean hours seated associated with a higher risk of venous thromboembolism. SAGE Publications 2016-08-01 /pmc/articles/PMC4973402/ /pubmed/27540486 http://dx.doi.org/10.1177/2054270416632670 Text en © The Author(s) 2016 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Research
Braithwaite, Irene
Healy, Bridget
Cameron, Laird
Weatherall, Mark
Beasley, Richard
Venous thromboembolism risk associated with protracted work- and computer-related seated immobility: A case-control study
title Venous thromboembolism risk associated with protracted work- and computer-related seated immobility: A case-control study
title_full Venous thromboembolism risk associated with protracted work- and computer-related seated immobility: A case-control study
title_fullStr Venous thromboembolism risk associated with protracted work- and computer-related seated immobility: A case-control study
title_full_unstemmed Venous thromboembolism risk associated with protracted work- and computer-related seated immobility: A case-control study
title_short Venous thromboembolism risk associated with protracted work- and computer-related seated immobility: A case-control study
title_sort venous thromboembolism risk associated with protracted work- and computer-related seated immobility: a case-control study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973402/
https://www.ncbi.nlm.nih.gov/pubmed/27540486
http://dx.doi.org/10.1177/2054270416632670
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