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Microwave assisted synthesis, antifungal activity, DFT and SAR study of 1,2,4-triazolo[4,3-a]pyridine derivatives containing hydrazone moieties

BACKGROUND: The increasing prevalence of multi-drug resistant fungal infections has encouraged the search for new antifungal agents. Hydrazone derivatives always exhibited diversity activities, including antifungal, anti-inflammatory, anti-oxidation, anti-cancer activity. Regarding the heterocyclic...

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Detalles Bibliográficos
Autores principales: Mu, Jin-Xia, Shi, Yan-Xia, Wu, Hong-Ke, Sun, Zhao-Hui, Yang, Ming-Yan, Liu, Xing-Hai, Li, Bao-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973519/
https://www.ncbi.nlm.nih.gov/pubmed/27493683
http://dx.doi.org/10.1186/s13065-016-0196-6