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Forward genetic screen of human transposase genomic rearrangements

BACKGROUND: Numerous human genes encode potentially active DNA transposases or recombinases, but our understanding of their functions remains limited due to shortage of methods to profile their activities on endogenous genomic substrates. RESULTS: To enable functional analysis of human transposase-d...

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Detalles Bibliográficos
Autores principales: Henssen, Anton G., Jiang, Eileen, Zhuang, Jiali, Pinello, Luca, Socci, Nicholas D., Koche, Richard, Gonen, Mithat, Villasante, Camila M., Armstrong, Scott A., Bauer, Daniel E., Weng, Zhiping, Kentsis, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973553/
https://www.ncbi.nlm.nih.gov/pubmed/27491780
http://dx.doi.org/10.1186/s12864-016-2877-x