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Neuronal cell-type-specific alternative splicing: A mechanism for specifying connections in the brain?

Alternative splicing (AS) allows a single gene to generate multiple protein isoforms. It has been hypothesized that AS plays a role in brain wiring by increasing the number of cell recognition molecules necessary for forming connections between neurons. Many studies have characterized isoform expres...

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Detalles Bibliográficos
Autores principales: Li, Joshua Shing Shun, Shin, Grace Ji-eun, Millard, S Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973604/
https://www.ncbi.nlm.nih.gov/pubmed/27606331
http://dx.doi.org/10.1080/23262133.2015.1122699