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Vaccinia Virus Infection Requires Maturation of Macropinosomes

The prototypic poxvirus, vaccinia virus (VACV), occurs in two infectious forms, mature virions (MVs) and extracellular virions (EVs). Both enter HeLa cells by inducing macropinocytic uptake. Using confocal microscopy, live‐cell imaging, targeted RNAi screening and perturbants of endosome maturation,...

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Detalles Bibliográficos
Autores principales: Rizopoulos, Zaira, Balistreri, Giuseppe, Kilcher, Samuel, Martin, Caroline K., Syedbasha, Mohammedyaseen, Helenius, Ari, Mercer, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons A/S 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973667/
https://www.ncbi.nlm.nih.gov/pubmed/25869659
http://dx.doi.org/10.1111/tra.12290