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Ribose 5-phosphate isomerase inhibits LC3 processing and basal autophagy

Autophagy and cellular metabolism are tightly linked processes, but how individual metabolic enzymes regulate the process of autophagy is not well understood. This study implicates ribose-5-phosphate isomerase (RPIA), a key regulator of the pentose phosphate pathway, in the control of autophagy. We...

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Detalles Bibliográficos
Autores principales: Heintze, Jacob, Costa, Joana R., Weber, Melanie, Ketteler, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973805/
https://www.ncbi.nlm.nih.gov/pubmed/27328773
http://dx.doi.org/10.1016/j.cellsig.2016.06.015