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Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling
Integrin dependent regulation of growth factor signalling confers anchorage dependence that is deregulated in cancers. Downstream of integrins and oncogenic Ras the small GTPase Ral is a vital mediator of adhesion dependent trafficking and signalling. This study identifies a novel regulatory crossta...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973806/ https://www.ncbi.nlm.nih.gov/pubmed/27269287 http://dx.doi.org/10.1016/j.cellsig.2016.05.023 |