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Cardiac-Restricted Expression of VCP/TER94 RNAi or Disease Alleles Perturbs Drosophila Heart Structure and Impairs Function

Valosin-containing protein (VCP) is a highly conserved mechanoenzyme that helps maintain protein homeostasis in all cells and serves specialized functions in distinct cell types. In skeletal muscle, it is critical for myofibrillogenesis and atrophy. However, little is known about VCP’s role(s) in th...

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Detalles Bibliográficos
Autores principales: Viswanathan, Meera C., Blice-Baum, Anna C., Sang, Tzu-Kang, Cammarato, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973812/
https://www.ncbi.nlm.nih.gov/pubmed/27500162
http://dx.doi.org/10.3390/jcdd3020019