Changes in protein structure monitored by use of gas‐phase hydrogen/deuterium exchange

The study of protein conformation by solution‐phase hydrogen/deuterium exchange (HDX) coupled to MS is well documented. This involves monitoring the exchange of backbone amide protons with deuterium and provides details concerning the protein's tertiary structure. However, undesired back‐exchan...

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Detalles Bibliográficos
Autores principales: Beeston, Helen S., Ault, James R., Pringle, Steven D., Brown, Jeffery M., Ashcroft, Alison E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Top down Intact Protein Analysis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973844/
https://www.ncbi.nlm.nih.gov/pubmed/25603979
http://dx.doi.org/10.1002/pmic.201400440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973844/
https://www.ncbi.nlm.nih.gov/pubmed/25603979
http://dx.doi.org/10.1002/pmic.201400440

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