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Molecular structure‐function relationship of dietary polyphenols for inhibiting VEGF‐induced VEGFR‐2 activity

1. SCOPE: We recently reported potent inhibition of VEGF signalling by two flavanols at sub‐micromolar concentrations, mediated by direct binding of the flavanols to VEGF. The aim of this study was to quantify the inhibitory potency and binding affinity of a wide range of dietary polyphenols and det...

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Detalles Bibliográficos
Autores principales: Cerezo, Ana B., Winterbone, Mark S., Moyle, Christina W. A., Needs, Paul W., Kroon, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973850/
https://www.ncbi.nlm.nih.gov/pubmed/26250940
http://dx.doi.org/10.1002/mnfr.201500407