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Estimation after subpopulation selection in adaptive seamless trials

During the development of new therapies, it is not uncommon to test whether a new treatment works better than the existing treatment for all patients who suffer from a condition (full population) or for a subset of the full population (subpopulation). One approach that may be used for this objective...

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Detalles Bibliográficos
Autores principales: Kimani, Peter K., Todd, Susan, Stallard, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973856/
https://www.ncbi.nlm.nih.gov/pubmed/25903293
http://dx.doi.org/10.1002/sim.6506