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Effects of a Soluble Epoxide Hydrolase Inhibitor on Lipopolysaccharide-Induced Acute Lung Injury in Mice

OBJECTIVES: Inflammation plays a key role in the pathogenesis of acute lung injury (ALI). Soluble epoxide hydrolase (sEH) is suggested as a vital pharmacologic target for inflammation. In this study, we determined whether a sEH inhibitor, AUDA, exerts lung protection in lipopolysaccharide (LPS)-indu...

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Detalles Bibliográficos
Autores principales: Tao, Wei, Li, Ping-Song, Yang, Liu-Qing, Ma, Yong-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973880/
https://www.ncbi.nlm.nih.gov/pubmed/27490848
http://dx.doi.org/10.1371/journal.pone.0160359