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Microarray-Based Analysis of Methylation of 1st Trimester Trisomic Placentas from Down Syndrome, Edwards Syndrome and Patau Syndrome

Methylation-based non-invasive prenatal testing of fetal aneuploidies is an alternative method that could possibly improve fetal aneuploidy diagnosis, especially for trisomy 13(T13) and trisomy 18(T18). Our aim was to study the methylation landscape in placenta DNA from trisomy 13, 18 and 21 pregnan...

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Detalles Bibliográficos
Autores principales: Hatt, Lotte, Aagaard, Mads M., Bach, Cathrine, Graakjaer, Jesper, Sommer, Steffen, Agerholm, Inge E., Kølvraa, Steen, Bojesen, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973974/
https://www.ncbi.nlm.nih.gov/pubmed/27490343
http://dx.doi.org/10.1371/journal.pone.0160319