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Fzd4 Haploinsufficiency Delays Retinal Revascularization in the Mouse Model of Oxygen Induced Retinopathy

Mutations in genes that code for components of the Norrin-FZD4 ligand-receptor complex cause the inherited childhood blinding disorder familial exudative vitreoretinopathy (FEVR). Statistical evidence from studies of patients at risk for the acquired disease retinopathy of prematurity (ROP) suggest...

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Detalles Bibliográficos
Autores principales: Ngo, Michael H., Borowska-Fielding, Joanna, Heathcote, Godfrey, Nejat, Sara, Kelly, Melanie E., McMaster, Christopher R., Robitaille, Johane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973993/
https://www.ncbi.nlm.nih.gov/pubmed/27489958
http://dx.doi.org/10.1371/journal.pone.0158320