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CO(2)-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture

Inflammation-induced release of prostaglandin E(2) (PGE(2)) changes breathing patterns and the response to CO(2) levels. This may have fatal consequences in newborn babies and result in sudden infant death. To elucidate the underlying mechanisms, we present a novel breathing brainstem organotypic cu...

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Detalles Bibliográficos
Autores principales: Forsberg, David, Horn, Zachi, Tserga, Evangelia, Smedler, Erik, Silberberg, Gilad, Shvarev, Yuri, Kaila, Kai, Uhlén, Per, Herlenius, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974055/
https://www.ncbi.nlm.nih.gov/pubmed/27377173
http://dx.doi.org/10.7554/eLife.14170