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CO(2)-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture
Inflammation-induced release of prostaglandin E(2) (PGE(2)) changes breathing patterns and the response to CO(2) levels. This may have fatal consequences in newborn babies and result in sudden infant death. To elucidate the underlying mechanisms, we present a novel breathing brainstem organotypic cu...
Autores principales: | Forsberg, David, Horn, Zachi, Tserga, Evangelia, Smedler, Erik, Silberberg, Gilad, Shvarev, Yuri, Kaila, Kai, Uhlén, Per, Herlenius, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974055/ https://www.ncbi.nlm.nih.gov/pubmed/27377173 http://dx.doi.org/10.7554/eLife.14170 |
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