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An oxygen-regulated switch in the protein synthesis machinery
Protein synthesis involves the translation of ribonucleic acid information into proteins, the building blocks of life. The initial step of protein synthesis consists of the eukaryotic translation initiation factor 4E (eIF4E) binding to the 7-methylguanosine (m(7)-GpppG) 5′cap of mRNAs(1,2). Low oxyg...
Autores principales: | Uniacke, James, Holterman, Chet E., Lachance, Gabriel, Franovic, Aleksandra, Jacob, Mathieu D., Fabian, Marc R., Payette, Josianne, Holcik, Martin, Pause, Arnim, Lee, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974072/ https://www.ncbi.nlm.nih.gov/pubmed/22678294 http://dx.doi.org/10.1038/nature11055 |
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