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Quantitative Cross-linking/Mass Spectrometry Using Isotope-labeled Cross-linkers and MaxQuant

The conceptually simple step from cross-linking/mass spectrometry (CLMS) to quantitative cross-linking/mass spectrometry (QCLMS) is compounded by technical challenges. Currently, quantitative proteomics software is tightly integrated with the protein identification workflow. This prevents automatica...

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Detalles Bibliográficos
Autores principales: Chen, Zhuo A., Fischer, Lutz, Cox, Jürgen, Rappsilber, Juri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974350/
https://www.ncbi.nlm.nih.gov/pubmed/27302889
http://dx.doi.org/10.1074/mcp.M115.056481