Pulmonary arterial hypertension associated with hereditary spherocytosis and splenectomy in a patient with a mutation in the BMPR2 gene

There is some question about the relationship between hereditary spherocytosis (HS) and pulmonary arterial hypertension, even associated with splenectomy. The finding of BMPR2 mutations in our patient suggests that other factors are necessary for the development of the disease, and perhaps, the inci...

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Autores principales: Baloira, Adolfo, Bastos, María, Pousada, Guillermo, Valverde, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974420/
https://www.ncbi.nlm.nih.gov/pubmed/27525076
http://dx.doi.org/10.1002/ccr3.610
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author Baloira, Adolfo
Bastos, María
Pousada, Guillermo
Valverde, Diana
author_facet Baloira, Adolfo
Bastos, María
Pousada, Guillermo
Valverde, Diana
author_sort Baloira, Adolfo
collection PubMed
description There is some question about the relationship between hereditary spherocytosis (HS) and pulmonary arterial hypertension, even associated with splenectomy. The finding of BMPR2 mutations in our patient suggests that other factors are necessary for the development of the disease, and perhaps, the incidence of pulmonary hypertension is not increased in patients with HS.
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spelling pubmed-49744202016-08-12 Pulmonary arterial hypertension associated with hereditary spherocytosis and splenectomy in a patient with a mutation in the BMPR2 gene Baloira, Adolfo Bastos, María Pousada, Guillermo Valverde, Diana Clin Case Rep Case Reports There is some question about the relationship between hereditary spherocytosis (HS) and pulmonary arterial hypertension, even associated with splenectomy. The finding of BMPR2 mutations in our patient suggests that other factors are necessary for the development of the disease, and perhaps, the incidence of pulmonary hypertension is not increased in patients with HS. John Wiley and Sons Inc. 2016-06-30 /pmc/articles/PMC4974420/ /pubmed/27525076 http://dx.doi.org/10.1002/ccr3.610 Text en © 2016 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Baloira, Adolfo
Bastos, María
Pousada, Guillermo
Valverde, Diana
Pulmonary arterial hypertension associated with hereditary spherocytosis and splenectomy in a patient with a mutation in the BMPR2 gene
title Pulmonary arterial hypertension associated with hereditary spherocytosis and splenectomy in a patient with a mutation in the BMPR2 gene
title_full Pulmonary arterial hypertension associated with hereditary spherocytosis and splenectomy in a patient with a mutation in the BMPR2 gene
title_fullStr Pulmonary arterial hypertension associated with hereditary spherocytosis and splenectomy in a patient with a mutation in the BMPR2 gene
title_full_unstemmed Pulmonary arterial hypertension associated with hereditary spherocytosis and splenectomy in a patient with a mutation in the BMPR2 gene
title_short Pulmonary arterial hypertension associated with hereditary spherocytosis and splenectomy in a patient with a mutation in the BMPR2 gene
title_sort pulmonary arterial hypertension associated with hereditary spherocytosis and splenectomy in a patient with a mutation in the bmpr2 gene
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974420/
https://www.ncbi.nlm.nih.gov/pubmed/27525076
http://dx.doi.org/10.1002/ccr3.610
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