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Genetically encoded protein photocrosslinker with a transferable mass spectrometry-identifiable label

Coupling photocrosslinking reagents with mass spectrometry has become a powerful tool for studying protein–protein interactions in living systems, but it still suffers from high rates of false-positive identifications as well as the lack of information on interaction interface due to the challenges...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Song, Haiping, He, Dan, Zhang, Shuai, Dai, Shizhong, Lin, Shixian, Meng, Rong, Wang, Chu, Chen, Peng R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974458/
https://www.ncbi.nlm.nih.gov/pubmed/27460181
http://dx.doi.org/10.1038/ncomms12299