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Peptide–oligonucleotide conjugates as nanoscale building blocks for assembly of an artificial three-helix protein mimic

Peptide-based structures can be designed to yield artificial proteins with specific folding patterns and functions. Template-based assembly of peptide units is one design option, but the use of two orthogonal self-assembly principles, oligonucleotide triple helix and a coiled coil protein domain for...

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Detalles Bibliográficos
Autores principales: Lou, Chenguang, Martos-Maldonado, Manuel C., Madsen, Charlotte S., Thomsen, Rasmus P., Midtgaard, Søren Roi, Christensen, Niels Johan, Kjems, Jørgen, Thulstrup, Peter W., Wengel, Jesper, Jensen, Knud J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974474/
https://www.ncbi.nlm.nih.gov/pubmed/27464951
http://dx.doi.org/10.1038/ncomms12294